VTN包被蛋白

Nuwacell™ -VTN包被蛋白（也称玻璃粘连蛋白，Vitronectin）是中盛溯源开发的一款化学成分明确，无异种成分的重组人蛋白。在无需饲养层培养人多能干细胞（hPSC）过程中，可以为细胞提供一层粘连表面，是目前大家所使用的基质胶（Matrigel）、人血浆来源的Vitronectin和标准的基底膜提取物（BME）的有效替代物。

Nuwacell™ VTN包被蛋白优势

✔ 成分明确，无异种成分

✔ 易于使用，可在室温下操作

✔ 兼容性好，可以与主流干细胞培养基配合使用

1、细胞形态与生长情况

Nuwacell™-VTN包被蛋白连续培养的hiPSC（P20）细胞形态图示。

图示别为培养第1、2、3天时，显微镜下hiPSC的形态图示，使用Nuwacell™ hiPSC/hESC 培养基-ncEpic培养。标尺:200μm。

2、文献引用

2020.03-Advanced Science（IF 15.804）-ESC‐sEVs Rejuvenate Senescent Hippocampal NSCs by Activating Lysosomes to Improve Cognitive Dysfunction in Vascular Dementia

Guowen Hu, et al. Advanced Science. 2020, 1903330.

2020.03-Cell Research(20.507)-Base editing-mediated splicing correction therapy for spinal

Xiang Lin, et al. Cell Research .2020, 0:1–3.

2020-Stem Cell Research& Therapy (IF 5.116)-Small extracellular vesicles secreted by human iPSC-derived MSC enhance angiogenesis through inhibiting STAT3-dependent autophagy in ischemic stroke

Yuguo Xia, et al. Stem Cell Research & Therapy. 2020,11(1):313.

2020-Journal of Extracellular Vesicles(IF 15.976)-Human ESC sEVs alleviate age related bone loss by rejuvenating senescent bone marrow derived mesenchymal stem cells

Liangzhi Gong, et al. Journal of Extracellular Vesicles. 2020,1800971.

2021.01-Ann Transl Med（3.297）-Transplantation of GMP-grade human iPSC-derived retinal pigment epithelial cells in rodent model- the first pre-clinical study for safety and efficacy in China.

Hang Zhang,et al.Ann Transl Med 2021.

2021.03-ACS Nano（14.588）-Embryonic Stem Cell Derived Small Extracellular Vesicles Modulate Regulatory T Cells to Protect against Ischemic Stroke.

Yuguo Xia,et al.ACS Nano. 2021.

细胞试剂

Media & Reagents

VTN包被蛋白